(15)模块2---认知症的心血管风险因素-Cardiovascular Risk Factors for Dementia-公开课-关爱惟士
(15)模块2---认知症的心血管风险因素-Cardiovascular Risk Factors for Dementia

课程视频 :http://player.youku.com/embed/XMjY3ODM2MDY4NA




Professor Kaarin Anstey

Kaarin Anstey教授


At a general level, we would say now that what is good for your heart is good for your brain. The vascular risk factors, things that influence your heart health or your vascular system, will also influence your vascular system in the brain, your cerebrovascular health. For example, hypertension is a risk factor for heart disease but it’s also a risk factor for stroke and for dementia.

一般我们会说,对你心脏好的东西也会对你的大脑好。影响你心脏健康或血管系统的血管因素也会影响你的脑血管系统和脑血管健康。例如高血压是心脏病的一个风险因素,但它也是中风和认知症的风险因素。


High cholesterol in midlife appears to, although we don’t have as robust evidence as we’d like on that, but from the evidence we do have, it seems to increase the risk. Diabetes, type 2 diabetes and type 1 both increase the risk. Sedentary lifestyle increases the risk, depression increases the risk. And depression is actually a cardiovascular risk factor, and very much linked with heart health, although it’s sometimes not considered a cardiovascular risk factor in the same way.

尽管我们还没有可靠的证据表明中年期的高胆固醇是风险因素,但我们已有的证据表明它似乎能够增加患认知症的风险。1型和2型糖尿病都能增加患病风险。久坐和抑郁症也能增加患病风险。抑郁症实际上是一个与心脏健康密切关联的心血管风险因素,虽然有时它不被人们认为是一个导致认知症的心血管风险因素。


We focus on the two most common types of causes of dementia, we have vascular dementia and Alzheimer's disease. Vascular dementia is caused by small strokes and large strokes and through hardening of the arteries. The risk factors that increase blood pressure and cause arthrosclerosis, they’re all going to increase the risk of vascular dementia. But, similarly, what’s being discovered more and more is that the vascular risk factors also increase Alzheimer's pathology in the brain. We don’t understand all the mechanism underpinning that, but they seem to increase that at the same time.


我们聚焦在血管性痴呆症和阿尔茨海默氏病这两种最常见的认知症的病因上。血管性痴呆症是由动脉硬化导致的多次大中风和小中风造成的。血压升高和关节内动脉硬化这些风险因素会增加患血管性痴呆症的风险。但是,同样这些血管风险因素也会增加患阿尔茨海默氏病的风险。我们尚未完全理解所有机制,但它们似乎同时增加患病风险。


翻译:关爱惟士-未经允许不得转载,违者必追究法律责任


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